Risks of grade reclassification among patients with Gleason grade group 1 prostate cancer and PI-RADS 5 findings on prostate MRI
Sundaresan V, Webb L, Rabil M, Golos A, Sutherland R, Bailey J, Rajwa P, Seibert T, Loeb S, Cooperberg M, Catalona W, Sprenkle P, Kim I, Leapman M. Risks of grade reclassification among patients with Gleason grade group 1 prostate cancer and PI-RADS 5 findings on prostate MRI. Urologic Oncology Seminars And Original Investigations 2024, 43: 193.e19-193.e26. PMID: 39706698, DOI: 10.1016/j.urolonc.2024.11.007.Peer-Reviewed Original ResearchConceptsPI-RADS 5 lesionsGG1 prostate cancerPI-RADSGG1 diseaseFusion biopsyRadical prostatectomyGleason gradeProstate cancerActive surveillanceGrade Group 1 prostate cancerSingle-institution retrospective analysisOptimal management of patientsMRI-ultrasound fusion biopsyLong-term outcome dataProstate Imaging ReportingMultivariate modelGenomic classifier scoresManagement of patientsPrimary study outcomeAssociated with upgradingMulti-institutional dataGleason upgradingTumor upgradingSurveillance biopsiesProstate MRI
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